Precision in Cellular Analysis

Flow cytometry, a technique that analyzes and quantifies cellular characteristics, has become an indispensable tool in fields ranging from biomedical research to clinical diagnostics. Known for their versatility and reliability, KNF Smooth Flow diaphragm pumps can play a critical role in enabling precise transfer and manipulation of cell samples within flow cytometry systems, replacing traditional methods.

Complexity Decoded

Complexity Decoded

Combining optics, fluidics, and sophisticated data analysis, flow cytometry enables researchers to uncover a world of cellular secrets with unparalleled precision and efficiency. From the identification of cell surface markers to the study of intracellular components, this method provides a comprehensive toolkit for exploring the intricacies of biological systems.

KNF Smooth Flow Technology for Sensitive Fluids

Fluid handling applications involving highly sensitive media, such as the sheath fluid used in flow cytometers, have typically relied on gear or peristaltic pumps. However, the unique Smooth Flow Technology developed for extremely low pulsation and used in the KNF FP liquid pump series has proven to be a superior alternative.

 

In flow cytometry, pumps already play a critical role in functions such as sample injection, sheath fluid delivery, waste fluid disposal, reagent delivery, as well as system priming and cleaning. There, the innovative Smooth Flow Technology has now made KNF diaphragm pumps the preferred choice for all these applications.

Minimizing Pulsation with Smooth Flow Pumps

The smooth flow of liquid pumps such as the FP 7 or FP 25 is achieved by integrated dampers. Other Smooth Flow pumps, such as the FP 150, create an exceptionally consistent flow by combining multiple diaphragms. This is achieved by interlacing the pulsations of the diaphragms to produce a very high, yet gentle, flow. Ideal for efficiently transferring fluids through long or small-diameter tubing, Smooth Flow pumps reduce pressure peaks and minimize tubing vibration.

Leading Innovation in Flow Cytometry

Integrating low-pulsation diaphragm pumps into flow cytometry systems offers several advantages that make them invaluable for cellular analysis and quantification. These include gentle sample handling, a wide range of fluid compatibility, self-priming, and dry-running capabilities.

Key Considerations for Flow Cytometry

Selecting the appropriate diaphragm pump for a specific flow cytometry application involves evaluating several criteria, such as flow rate requirements, pressure capabilities, fluid compatibility, and desired performance characteristics.
 
KNF offers a wide range of state-of-the-art diaphragm pump models, each designed to meet specific needs and ensure optimal sample transport and analysis. Proper system design minimizes dead volume, reduces sample carryover, and ensures efficient sample delivery to the analysis chamber. By choosing the right KNF diaphragm pump and through a variety of customization options, engineers and scientists can improve the accuracy and reliability of their flow cytometry results and ensure precise and efficient sample processing.

How KNF Can Support the Drive for Innovation

In modern flow cytometry, reliable and high-performance pump solutions play a critical role in enabling precise analysis of the composition, morphology, and functions of entire cell populations in a matter of seconds, ultimately improving the efficiency and accuracy of cellular studies.

Get in touch with us to find out how our experts can help you improve your flow cytometry technology.

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