KNF Diaphragm Pumps Critical in Degassing for Chromatography, Inkjet Applications

A Complex Process Used in HPLC Applications

HPLC differs from more traditional liquid chromatography because it requires significantly higher operational pressure to pass liquids through the mobile phase. It is an incredibly delicate and complex process for liquid mixture analysis. HPLC has applications in a variety of industries, including pharmaceutical development, research, and medical applications. It even has uses in legal and criminal justice applications.

Degassing is an integral part of the HPLC process. Actively removing gases from the liquid mixtures being transferred during the mobile phase is necessary for sample accuracy. It prevents the buildup of bubbles in the detector while also improving baseline stability. Degassing reduces the amount of solvent released into the atmosphere. It also helps improve the performance of the liquid pumps involved in the system, leading to less cavitation.  

Quality Inkjet Printing Performance Depends on Degassing

Gases in the system can drastically impact the performance of Inkjet printing systems. Bubbles in the ink can cause interruptions with flow and lead to shortages in the print heads. In some cases, it can lead to foaming, causing further interruptions in ink flow. Proper degassing can lead to improved speeds and smoother operation, with better quality outputs. It can also help reduce printer downtime.           

Degassing Processes Requires Specialized Pumps 

The right diaphragm gas pump is important for degassing applications. The pumps in question must meet strict standards to operate effectively. Whether it’s for HPLC or Inkjet applications, degassing pumps need to have two connected heads and run at high speeds initially before having their motor rpms gradually reduced to ensure desired vacuum level. The ability to handle condensate is also critical, as any condensate that passes through the degasser will eventually pass through the pump. KNF pumps can be fitted with gas ballasts to help remove condensate from the system. They need to achieve a vacuum below 100 mbar while also outputting minimal noise. All of this while maintaining a constant vacuum level with a diaphragm made from solvent resistant materials.

KNF Offers Multiple Options for HPLC Pumps

The NMP 830.3 version is an excellent diaphragm pump option for degassing. This two-headed pump offers a maximum vacuum down to 55 mbar (abs.) and provides excellent reliability in a compact size. Its valve system allows for proper handling of condensates, and it is available with a custom, chemically resistant PTFE diaphragm upon request. It can also be fitted with an optional gas ballast. The NMP 830.3 comes with a digitally adjustable brushless DC motor for full parameterization and precise speed control. It can be preprogrammed to a defined vacuum level, which can be controlled with a closed loop system during operation. The pump runs at a low sound level and provides strong performance without contaminating media.

The N 84.3 is also a strong choice for degassing operations. It has a maximum vacuum of 7 mbar (abs.) with a maximum flow rate of 5 l/min. It offers a PTFE-coated diaphragm and is available with a speed-controlled brushless DC motor. The N 84.3 offers quiet operation and a high flow rate at deep vacuum.